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July 17th 2017
"Biocatalytic synthesis of acrylonitrile from renewable raw materials" is the subject of a joint FNR-funded research project of Dralon GmbH and Enzymicals AG >more

July 06th 2017
Christian Pegel, Minister of Energy, Infrastructure and Digitization of the State Government of Mecklenburg-Western Pomerania, visited Enzymicals AG during a visit to the Biotechnikum Greifswald on 05th of July 2017 >more

June 20th 2017
What's behind the name Enzymicals? The CEO, Dr. Ulf Menyes answered this and other questions in an interview with "Laborjournal". >more

May 10th 2017
Enzymicals is one of the eight companies out of Middle German fine chemistry region, which present their expertise together at one joint booth at Chemspec Europe 2017 in Munich. >more

April 26th 2017
Dr. Henrike Brundiek ist the new Head of R&D at Enzymicals AG:
Dr. Brundiek is a long-term employee of Enzymicals AG and takes over the scientific management of the company from now on. The former CSO, Dr. Rainer Wardenga, steps down from the managing board due to a longer-term parental leave. This decision was made by mutual agreement between the bodies of Enzymicals AG and reflects the family-friendliness of the company. >more

April 13th 2017
Enzymicals has been a member of the network 4chiral since 28.03.2017. With the slogan "Our core competence in organic synthesis", the network is conducting research and development projects in the field of organic synthesis. Enzymicals is now expanding the possibilities of the network by its expertise in the application of enzymatic processes for the synthesis of complex chemicals.

March 23th 2017

Sequential multistep one-pot reaction

Dr. Melinda Fekete, senior scientist at Enzymicals, has participated at a workshop which was focused on "Chemical Development and Scale-Up in the Fine Chemical and Pharmaceutical Industries". There she had the opportunity to discuss the activities of Enzymicals in this field using the Carbazymes project.

March 20th 2017
Enzymicals AG congratulates its long-standing network partner Herbrand PharmaChemicals GmbH for the acquisition of an 11-hectare site near Anklam in the northeast of Germany. (Read more) The creation of a new production site close to Enzymicals AG, improves the possibilities of these two synergistic acting companies to offer unique chemo-enzymatic solutions in the field of fine chemicals.

February 16th 2017
The article on "Efficient Chiral Chemistry by Application of Stereoselective Biocatalysts in Micro-Aqueous Reaction Systems", published in the February issue of "Specialty Chemistry Magazine", is another proof of the fruitful collaboration of Enzymicals with the group of Prof. Dörte Rother from FZ Jülich.

January 25th 2017
Prof. Fessner, coordinator of the CarbaZymes project, launched in April 2016 and funded by the EU at EUR 8.2 million, reported in an interview on the first successes and the challenges ahead. The aim of the project, for which Enzymicals also works intensively, is the development of enzymes for the formation of carbon-carbon bonds and the transfer into robust processes on an industrial scale to produce selected products. (See animation)

December 05th 2016
A new 4 x 1L multi-reactor system and a plant for the chromatographic purification of proteins on a preparative scale have been put into operation. This enables Enzymicals AG to optimize biocatalytic processes faster and more efficient and to meet customers' needs for purified proteins.

October 20th 2016
Enzymicals industrial collaborations result in real products and processes as well scientific articles. The outcome of currently performed projects with the companies Merck and Herbrand are published in high level journals. See more in our section abstract service.

September 26th 2016
Enzymicals coverage about its new phosphotransferases in a newsletter story on Manufacturing Chemist.

September 06th 2016
The new catalog Enzymicals is available!
The portfolio has been extended by Phosphotransferases for producing specific metabolites and two other halohydrin dehalogenase, for example, for the synthesis of 1,2-amino alcohols.

August 18th 2016
The news channel N24 has presented Enzymicals with a short profile in "Extra tip Business" as one of the most innovative SMEs in Mecklenburg-Vorpommern.

June 23th 2016
Enzymicals fur­ther expand its capacities for up-scaling and pi­loting of biocat­alyt­ic processes. Through the success in fiscal year 2015 and in current projects, signif­icant invest­ments in technical equip­ment connected with structural exten­sions are currently be­ing re­alized. Thereby, the devel­op­ment of opti­mized biocat­alyt­ic processes and its transfer to pi­lot scale is signif­icantly more ef­fective than it was pre­vi­ously pos­sible.

April 22nd 2016
Enzymicals has devel­oped a new simple and ro­bust way to manufac­ture enantiopure Rimanta­dine. For this process, Transam­inases from the internal portfo­lio of the compa­ny are used. (Fur­ther information)

March 18th 2016
Enzymicals supports as a sponsor the internationally renowned Gordon Research Conference first time. The guiding theme this year is "Creative Science and processes for biocatalysis".

January 18th 2016
Enzymicals has included imine reductases (IREDs) as a new class of enzymes in the cat­a­log. With cat­a­log update in Jan­uary the offer of chem­icals has been ex­tended at 5 chiral com­pounds.

October 26th 2015

Sequential multistep one-pot reaction

The devel­op­ment of a chemoenzymat­ic process for the production of (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carboxylic acid by recombinant pig liv­er esterase in an opti­mized enantios­e­lective sequential mul­ti­s­tep one-pot re­action is presented in Org. Process Res. Dev. DOI 10.1021/acs.oprd.5b00294

September 23th 2015
Am­ine transam­inases of Enzymicals are used in a nov­el two-step biocat­alyt­ic route for production of all four stereoiso­mers of nor(pseuso)ephedrine. Currently, the technology is trans­ferred to the production. (see Manufacturing Chemist, Vol 86, No 9, pp 47-48)

July 27th 2015
Puro­lite and Enzymicals have devel­oped a screening kit with five im­mobi­lized R-se­lective transam­inases that show broad substrate range and ex­cel­lent enantios­e­lectiv­ity. The joint commercialization starts this week at Biotrans-Confer­ence in Vi­enna. (See flyer)

June 4th 2015
"Enzymicals transfers indus­trially useful cat­a­lysts to pharma inter­me­diate application" is the current Newletterstory in Manufac­tur­ing Chemist.

May 21th 2015
From now on the syn­thet­ic nicot­i­n­am­ide ana­logue BNAH is avail­able at En­zym­ic­als. At first the pro­duc­tion of cofactor sub­sti­tute was op­tim­ized and es­tab­lished for ap­plic­a­tion in biocata­lyt­ic syn­thes­is by Dr. Holl­mann at Uni­versity of Delft. Now, En­zym­ic­als real­ize the com­mer­cial­iz­a­tion. From June BNAH will be avail­able via the cata­log.

June 4th 2015
"Enzymicals transfers industrially useful catalysts to pharma intermediate application" is the current Newletterstory in Manufacturin Chemist.
(press release)

March 30th 2015
En­zym­ic­als is a con­sor­ti­um part­ner in three pro­jects of the H2020-fund­ing peri­od. With these pro­jects a total of € 1.2 mil­lion grants were pro­cured for En­zym­ic­als.
(press release)

March 23th 2015
A cur­rent com­pany pro­file of En­zym­ic­als was pub­lished in the newly re­leased 5th edi­tion of the "European Bi­o­tech­no­logy Guide".

March 05th 2015
Sim­ul­tan­eous to the Con­fer­ence "Transam 2.0 - Chir­al Amines Through (Bio) Cata­lys­is" which takes place in Gre­if­swald from 03th to 05th of March, En­zym­ic­als brings a new screen­ing kit in first gen­er­a­tion with sev­en im­mob­il­ized R-se­lect­ive transa­m­inases on the mar­ket. This kit was de­veloped in col­lab­or­a­tion with Pur­ol­ite. The kit is avail­able on re­quest.

February 04th 2015
On the DE­CHEMA PRAX­IS­for­um "En­zymes for In­dus­tri­al Ap­plic­a­tions" En­zym­ic­als presents a pro­cess for Desym­met­riz­a­tion of meso-1,2-Di­esters. Us­ing a pig liv­er isoen­zyme a ro­bust and ef­fi­cient pro­cess has been de­veloped and up­scaled up to the kilo­gram scale.

December 15th 2014
Enzymicals provide one PhD-position in the context of BIOCASCADES Marie Curie Innovative Training Network for European Industrial Doctorates (ITN-EID). This is an interdisciplinary research and training network of 7 universities and 5 industrial enterprises from 5 European countries.

October 14th 2014

GründerChampions 2014


En­zym­ic­als has won the cor­por­ate com­pet­i­tion KfW Award Gründer­Cham­pi­ons in 2014 in the state of Mecklen­burg-West­ern Pom­er­a­nia. The prize is awar­ded in the frame­work of the Ger­man Founders and En­tre­pren­eurs days (deGUT). The fest­ive award ce­re­mony will take place on Oc­to­ber 16th at the Fed­er­al Min­istry of Eco­nom­ics and Tech­no­logy in Ber­lin.



September 16th 2014
Prof. Uwe Bornsch­euer, the found­ing fath­er of En­zym­ic­als was awar­ded by the Ger­man So­ci­ety for Fat Sci­ence e.V. (DGF) with the "Wil­helm-Nor­mann-Medal". The award ce­re­mony took place this week at the EuroFed­Lip­id con­fer­ence.

September 10th 2014
Be­gin­ning of Septem­ber in Ham­burg took place the 7th In­ter­na­tion­al Con­gress on Biocata­lys­is. At the con­gress En­zym­ic­als has very suc­cess­fully presen­ted a lec­ture on the top­ic "Scale-up of a re­com­bin­ant pig liv­er es­terase-cata­lyzed desym­met­riz­a­tion of di­methyl cyc­lo­hex-4-ene-cis-1,2-di­carboxylate". Ad­di­tion­al res­ults were presen­ted at two posters on the top­ics "Pro­duc­tion of nov­el halo­hydrin de­halo­genases for the syn­thes­is of ß-sub­sti­tuted al­co­hols" and "Syn­thes­is of fine chem­ic­als with re­com­bin­ant iso­forms of pig liv­er es­terase".

August 18th 2014
We cel­eb­rate our 5th birth­day. The team of En­zym­ic­als which now con­sists of 14 col­leagues, cel­eb­rated the fifth com­pany ju­bilee with a trip to the is­land Vilm. (More in­form­a­tion at Bi­otec-find­er)
Document

July 29th 2014
En­zym­ic­als has de­veloped and scaled up a ro­bust biocata­lyt­ic pro­cess for desym­met­risa­tion of a meso-di­ester. As cata­lyst was used a re­com­bin­antly pro­duced pig liv­er es­terase isoen­zyme. A pa­per which de­scribed the pro­cess de­vel­op­ment was pub­lished in Man­u­fac­tur­ing Chem­ist.

July 24th 2014
En­zym­ic­als presen­ted a poster with new­est res­ults on its in­vest­ig­a­tions on halo­hydin de­halo­genases very suc­cess­ful at Gor­don Re­search Con­fer­ence in Spring­field, USA.

July 14th 2014
Most re­cently for three Baey­er-Vil­li­ger monooxy­genases is a new li­quid for­mu­la­tions in the cata­log. This will greatly en­hance the sta­bil­ity of this en­zymes.

June 12th 2014
The Work­ing Group Phar­ma­ceut­ic­al Bi­o­tech­no­logy at the Uni­versity of Gre­if­swald and the En­zym­ic­als co­oper­ate in a re­search pro­ject to pro­duce ef­fi­ciently re­com­bin­ant en­zymes in newly de­veloped Ba­cil­lus strains with QPS status in in­dus­tri­al scale. (idw – In­for­ma­ti­ons­dienst Wis­sen­schaft)

June 04th 2014
Enzymicals AG acts on international markets: Intellectual Property Rights for recombinant isoforms of pig liver esterases (PLE) granted in Japan
Document

May 28th, 2014
Enzymicals expanded its patent position in Asia. End of May, the Japanese Patent Office granted the rights for certain isoforms of pig liver esterases. (Transkript 6/2014 p.10)
Document

April 29th 2014
In the is­sue 1/2014 of the magazine Life Sci­ence Nord En­zym­ic­als AG is rep­res­en­ted as "the per­fect part­ner". The magazine was pub­lished to the Ger­man Bi­o­tech­no­logy Days in April. The art­icle on page 17 shows how it is pos­sible for En­zym­ic­als to cov­er the whole value chain of White bi­o­tech­no­logy.

March 10th 2014
"Tail­or-made solu­tions for biocata­lyt­ic ap­plic­a­tions for every­one in chem­istry?" – This ques­tion and the con­tri­bu­tion of En­zym­ic­als in this field is the sub­ject of the March is­sue of the e-news­let­ter of Man­u­fac­tur­ing Chem­ist.

Decem­ber 12th 2013
In the an­nu­al 2013/2014 from Bio Deutsch­land e.V. a guest art­icle from DBU (Deutsche Bundess­tif­tung Um­welt) was pub­lished. This art­icle de­scribes the pro­ject "e-Capro­lac­tone-pro­duc­tion us­ing mo­lecu­lar oxy­gen". En­zym­ic­als makes an im­port­ant con­tri­bu­tion for this pro­ject which is sup­por­ted by the DBU.

May 23th, 2013
An actual company profile was published in the new edition of the "15th Guide to German Biotech Companies".
Company profile

April 18th, 2013
The new biotechnology report from Ernst & Young is published. There you can find an article about the capability of Enzymicals.

Document
June 18th 2012
Braun Beteiligungs GmbH (BBG) has acquired a stake in Enzymicals AG to facilitate a stronger collaboration between Enzymicals AG, Herbrand PharmaChemicals GmbH and BRAIN AG.
Document - Image

February 28th, 2012
Enzymicals AG forged links in Philadelphia within a marketing aid program of the German Federal Ministry of Economics.
Document - Image

January 17th, 2012
Enzymicals AG and Herbrand PharmaChemicals GmbH cooperate for biotechnological production of pharmaceuticals and intermediates.
Document - Image 1 - Image 2

Juni 21st, 2011
Enzymicals AG and Lonza AG sign license agreement for the global use of (R)-selective transaminases in laboratory scale in Lonza patented processes.
Document - Image 1 - Image 2

June 1st, 2011
White meets blue. Die Enzymicals AG und das Institut für Marine Biotechnologie e.V. kooperieren in der weißen und blauen Biotechnologie.
Document - Image 1

October 4th, 2010
Enzymicals AG acquires proprietary rights on pig liver esterases (PLE) from Evonik AG.
Document - Image 1

July 12th, 2010
BRAIN AG acquires share in chemical and biocatalyst specialist Enzymicals AG.
Document - Image 1 - Image 2 - Image 3

Enzymicals in den Medien

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transkript 8-9/2012
The Brainzymicalsbraun AG
Article

transkript

ChemBioTec Review 003
Company profile
Article (available in German)

transkript

transkript 8-9/2010
BRAIN invests in fine chemicals specialist
Article (available in German)

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BIOspektrum 06.10
Enzymicals AG: Academic spin-off with high ambitions
Article (available in German)