We believe that quality and compliance of facilities and products are one of the key mechanisms in providing services and products that are competitive, innovative and exceed customer expectations. Our Quality System covers services and business functions. Our risk analysis technique and procedures cover all production processes, from the start-up of a project to the production and distribution of materials. Our teams are dedicated to continuous improvement, to meet customer expectations and maintain customer confidence.
If new manufacturing processes were the foundation of the original industrial revolution, ‘biomanufacturing’ will be the bioeconomy’s equivalent. We use the concept of in-vitro biosynthesis to produce diverse consumer products.
Enzymes can be much more selective than other catalysts, meaning they can produce more of the desired product and less undesired by-products. In early phase evaluations, we analyze if enzyme-based catalysis has a clear advantage over its alternatives. In addition to constant demands for unbeatable stereoselectivity, this is often the case in dealing with complex molecules or late-stage functionalizations with a strong demand for regioselectivity. In particular, non-productive synthesis steps which only serve to protect functional groups or to activate non-reactive groups can often be bypassed. This shortens synthetic routes and generate fewer by-products, which enables more efficient and resource-saving manufacturing processes.
A key aspect of nature’s synthetic strategy are cascade sequences of biotransformations. We use and apply this to enable super-efficient multi-step reactions by a variety of biocatalytic one-pot systems to build complex molecules from simple starting materials. In combination with innovative membrane reactor techniques and in-situ crystallization based downstream methods, our continuous processes lead to increased resource & energy efficiency with decreased investment & operating costs and a currently urgently needed decreased environmental footprint.
DBU Alliance ChemBioTec: Sustainable biocatalytic oxidation processes. 2011 – 2014
EU FP7: NewProt An interactive protein engineering portal. 2011 – 2015
Biocatalysis 2021: New developments for industrial white biotechnology. 2012 – 2015
SME Innovation program: Production of fine chemicals with recombinant porcine liver esterases. 2012 – 2015
DBU Integrated Biotechnology: Biocatalytic synthesis of functionalized chiral amines by transaminases. 2012 – 2015
SME Innovation program: Sustainable processes for the production of chemically beta-substituted alcohols by novel halohydrin dehalogenases. 2013 – 2015
European Fund for Regional Development: New Bacillus expression and secretion systems for the production of industrial enzymes. 2013 – 2015
Strategic Alliance ZeroCarbFP: Functional biomass from carbon-rich waste streams. 2013 – 2016
EuroTransBio: Bio-based detergents for domestic and industrial washing applications. 2014 – 2017
SME Innovation program: Sustainable synthesis of chiral α-hydroxyketones by coupled enzymatic and chemical catalysis. 2014 – 2017
MSCA-ITN-EID: Sustainable and scalable biocatalytic cascade reactions. 2015 – 2018
EU Horizon2020: Sustainable industrial processes based on a C-C bond-forming enzyme platform. 2015 – 2019
EU Horizon2020: Adding value to camelina and crambe oil. 2015 – 2019
Agency for Renewable Resources: Biocatalytic synthesis of acrylonitrile from renewable resources. 2017 – 2019
EU Horizon2020: Upcycling of PE and PET wastes to generate biodegradable bioplastics for food and drink packaging. 2019 – ongoing
EU Horizon2020: Membranes And Catalysts Beyond Economic and Technological Hurdles. 2019 – ongoing
BMBF Bioeconomy at marine sites: Enzymatic synthesis of marine sugars. 2019 – ongoing
Innovation alliance Plant³: Regional use of macroalgae from the Baltic Sea coast as a renewable resource for a bio-based economy. 2019 – ongoing
SME Innovation program: Biosynthesis of baclofen and related compounds. 2019 – ongoing
SME Innovation program: In-situ crystallization concepts for transaminase reactions. 2019 – ongoing